differentiation 31 cd31 affinity purified polyclonal ab (R&D Systems)
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Differentiation 31 Cd31 Affinity Purified Polyclonal Ab, supplied by R&D Systems, used in various techniques. Bioz Stars score: 98/100, based on 1263 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 98 stars, based on 1263 article reviews
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1) Product Images from "Vascular regional analysis unveils differential responses to anti-angiogenic therapy in pancreatic xenografts through macroscopic photoacoustic imaging"
Article Title: Vascular regional analysis unveils differential responses to anti-angiogenic therapy in pancreatic xenografts through macroscopic photoacoustic imaging
Journal: Theranostics
doi: 10.7150/thno.99361
Figure Legend Snippet: A) 2D cross sectional US image in a representative MIA PaCa-2 tumor. B) H&E stain of the same tumor cross section shown in A,C. C) 2D cross sectional image of HbT overlayed on US in a representative MIA PaCa-2 tumor with white arrows pointing towards areas of HVD and yellow arrows pointing towards areas of LVD. D) IF stain of the same tumor cross section shown in A,C with blue representing DAPI and red representing CD31. White arrows pointing towards areas of HVD and yellow arrows pointing towards areas of LVD according to the HbT image. E) Plot of normalized average CD31 intensity in a 1 mm x 1 mm ROI versus the fraction of pixels in the ROI labelled as HVD. All scale bars shown represent 2 mm.
Techniques Used: Staining
Figure Legend Snippet: A-B) Representative AsPC-1 tumors stained for CD31 (red) and αSMA (green) overlaid on DAPI (blue) for the control (A) and sunitinib (B) treated group. C) Bar graph comparing αSMA + / CD31 + cell ratio between the control (black) and sunitinib (red) groups. D-E) Representative MIA PaCa-2 tumors stained with CD31 (red) and αSMA (green) overlaid on DAPI (blue) for the control (D) and sunitinib (E) treated group. F) Bar graph (Mean +/- SEM) comparing αSMA + / CD31 + cell ratio between the control (black) and sunitinib (red) groups for MIA PaCa-2. G-H) Scatter plot of αSMA + / CD31 + versus the HVD ∆StO₂ between D(8) and D(-1) (G) HVD fraction on D(8) (H) for each histological sample with points corresponding to MIA PaCa-2 tumors outlined in green, and AsPC-1 tumors outlined in blue. I-J) Representative AsPC-1 tumors stained for CD31 (red) and TL (green) overlaid on DAPI (blue) for the control (I) and sunitinib (J) treated group. K) Bar graph comparing TL + / CD31 + cell ratio between the control (black) and sunitinib (red) groups. L -M) Representative MIA PaCa-2 tumors stained with CD31 (red) and TL (green) overlaid on DAPI (blue) for the control (L) and sunitinib (M) treated group. N) Bar graph comparing TL + / CD31 + cell ratio between the control (black) and sunitinib (red) groups for MIA PaCa-2. O-P) Scatter plot of ΤL + / CD31 + versus the HVD ∆StO₂ between D(8) and D(-1) (O) HVD fraction on D(8) (P) for each histological sample with points corresponding to MIA PaCa-2 tumors outlined in green, and AsPC-1 tumors outlined in blue. It is to be noted that all four stains DAPI, TL, αSMA and CD31 are performed on the same section. For display purposes we showed DAPI, TL, CD 31 and DAPI, αSMA and CD31 images separately. All scale bars = 125 μm, All error bars shown represent SEM. p-values: * < 0.05, ** < 0.01, *** < 0.001
Techniques Used: Staining, Control
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